{"id":53,"date":"2026-10-15T14:00:38","date_gmt":"2026-10-15T14:00:38","guid":{"rendered":"https:\/\/hcu-kompass.de\/?page_id=53"},"modified":"2026-10-15T14:00:38","modified_gmt":"2026-10-15T14:00:38","slug":"forschung","status":"publish","type":"page","link":"https:\/\/hcu-kompass.de\/?page_id=53","title":{"rendered":"Forschung &#038; Neues"},"content":{"rendered":"\n<div class=\"wp-block-group is-style-kid is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Auf der ganzen Welt arbeiten Forscherinnen und Forscher daran, eine neue Ersatz-Maschine f\u00fcr deine Fabrik zu bauen. Sie wird gerade getestet. Vielleicht wird dein Essen sp\u00e4ter einmal einfacher.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-timeline is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">2017<\/p>\n\n\n<h3 class=\"wp-block-heading\">Europ\u00e4ische Leitlinie<\/h3>\n\n\n<p class=\"wp-block-paragraph\">Das Netzwerk E-HOD ver\u00f6ffentlicht Empfehlungen zu Diagnose und Behandlung. Zielwert: Homocystein unter 100 \u00b5mol\/L.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-timeline is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Januar 2025<\/p>\n\n\n<h3 class=\"wp-block-heading\">Registerauswertung mit 311 Patienten<\/h3>\n\n\n<p class=\"wp-block-paragraph\">Die meisten Non-Responder wurden mit Betain und Di\u00e4t behandelt, viele bekamen aber trotzdem B6, teils in gef\u00e4hrlich hohen Dosen.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-timeline is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Mai 2025<\/p>\n\n\n<h3 class=\"wp-block-heading\">Neugeborenenscreening wird erweitert<\/h3>\n\n\n<p class=\"wp-block-paragraph\">Der G-BA beschlie\u00dft: Homocystinurie, Vitamin-B12-Mangel, Propionazid\u00e4mie und Methylmalonazidurie kommen hinzu, angewendet ab Mai 2026.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-timeline is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Oktober 2026<\/p>\n\n\n<h3 class=\"wp-block-heading\">Enzymersatz Pegtibatinase in Phase 3<\/h3>\n\n\n<p class=\"wp-block-paragraph\">Die HARMONY-Studie testet ein Ersatz-Enzym als Spritze unter die Haut, f\u00fcr Betroffene von 12 bis 65 Jahren. In der fr\u00fcheren Studie sank Homocystein bei der h\u00f6chsten Dosis um 57\u201367 %.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-timeline is-future is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">2. H\u00e4lfte 2027<\/p>\n\n\n<h3 class=\"wp-block-heading\">Erste HARMONY-Ergebnisse erwartet<\/h3>\n\n\n<p class=\"wp-block-paragraph\">Hersteller Travere rechnet dann mit den Hauptergebnissen. Ob und wann eine Zulassung folgt, ist offen.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-style-note is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Studien zu Homocystinurie findet ihr im <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT06247085\" target=\"_blank\" rel=\"noopener\">Studienregister ClinicalTrials.gov<\/a> und im europ\u00e4ischen Register. Fragt euer Zentrum, ob eine Studie f\u00fcr euer Kind in Frage kommt.<\/p>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>Was sich bei Diagnose und Behandlung der Homocystinurie gerade bewegt.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-53","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=\/wp\/v2\/pages\/53","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=53"}],"version-history":[{"count":0,"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=\/wp\/v2\/pages\/53\/revisions"}],"wp:attachment":[{"href":"https:\/\/hcu-kompass.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=53"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}